Syphilis is treated with antibiotics. If you have been infected for less than a year, your doctor will give you a single injection of penicillin. However, you may need some extra injections over the course of several days if you have had syphilis for a year or more. Sometimes your doctor may prescribe antibiotic tablets for you instead of injections. If you are allergic to penicillin, your doctor will give you an alternative antibiotic.
Attribution: BUPA