Medicines are the most effective treatment for most people with Crohn's disease. Commonly used medicines are Aminosalicylates- to treat milder inflammation or reduce the chances of a flare-up, corticosteroids can help reduce inflammation, these are effective but can only be used for a short time during a flare-up because they can cause serious side effects, medicines to suppress your immune system can help to reduce inflammation once you have stopped taking steroids. Antibiotics can help to reduce bacteria in your bowel or treat abscesses. If you need to take painkillers you shouldn't take non-steroidal anti-inflammatory medicines(NSAIDs), eg ibuprofen. These can cause a flare-up of Crohn's disease. It's usually fine to take paracetamol as a painkiller but check with your doctor first.
Attribution: BUPA