Adherence means taking your ARVs on time every day. You need to be almost 100% adherent to stay healthy, even if you experience side effects. There is about an hour gap within which you should take them. The first time you use ARVs is when the drugs are likely to work best. Just missing one or 2 doses a week will lead to problems. If you forget and only remember at your next dose do not take a double dose!
Attribution: Straight Talk Foundation & Marie Stopes